The Large Synoptic Survey Telescope (LSST) is currently under construction and upon completion will perform precision photometry over the visible sky at a 3-day cadence. To meet the stringent relative photometry goals, LSST will employ multiple calibration systems to measure and compensate for systematic errors. This paper describes the design and development of these systems including: a dedicated calibration telescope and spectrograph to measure the atmospheric transmission function, a collimated beam projector to characterize the spatial dependence of the LSST transmission function and an at-field screen illumination system to measure the high-frequency variations in the global system response function.